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Within the scientific trial expertise with Xyrem in narcolepsy/cataplexy people at therapeutic doses, two individuals claimed panic and 1 described sleeplessness pursuing abrupt discontinuation within the termination of the medical trial; in the two sufferers with panic, the frequency of cataplexy had greater markedly concurrently.

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g., assault sufferer). Illicit GHB is abused in social settings principally by young Older people. A few of the doses estimated being abused are in an identical dosage array to that useful for therapy of people with cataplexy.

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Sufferers will frequently fall asleep inside of 5 minutes of getting Xyrem, and will often slide asleep inside 15 minutes, however some time it's going to take any person patient to tumble asleep may possibly vary from evening to night.

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Prepare both of those doses of Xyrem ahead of bedtime. Previous to ingestion, each dose of Xyrem need to be diluted with around ¼ cup (somewhere around sixty mL) of water while in the empty pharmacy vials furnished.

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